Viral aggregation: quantitation and kinetics of the aggregation of poliovirus and reovirus
- 1 June 1978
- journal article
- research article
- Published by American Society for Microbiology in Applied and Environmental Microbiology
- Vol. 35 (6), 1079-1083
- https://doi.org/10.1128/aem.35.6.1079-1083.1978
Abstract
The aggregation of poliovirus and reovirus was followed in buffers at various pH values by means of a single particle analysis (SPA) test. The SPA test used here was modified from the original test reported earlier to prevent disaggregation of virus clumps from invalidating the results. The modified SPA test demonstrated that the efficiency of aggregation, which is a measure of the percentage of collisions which are effective in producing an aggregate, may vary widely depending on the conditions in which the virus is placed. The modified SPA test was also used to demonstrate that the kinetic features of viral aggregation follow the classical laws of colloid particle aggregation, which in turn are solely dependent upon diffusion of the particles as caused by brownian motion.This publication has 4 references indexed in Scilit:
- Aggregation of poliovirus and reovirus by dilution in waterApplied and Environmental Microbiology, 1977
- Initial fast reaction of bromine on reovirus in turbulent flowing waterApplied and Environmental Microbiology, 1976
- Inactivation by bromine of single poliovirus particles in waterApplied and Environmental Microbiology, 1976