CLINICAL ASPECTS OF POLYCYSTIC OVARY SYNDROME
- 1 January 1977
- journal article
- research article
- Vol. 49 (5), 552-556
Abstract
Patients (101) with polycystic ovary syndrome (PCO) were treated during an 11 yr interval. Cases (67) were classified as typical PCO with enlarged ovaries of probable ovarian origin (Type I) and 34 as atypical PCO of probable adrenal origin (Type II). Patients (55) were treated for anovulatory infertility with clomiphene citrate or other endocrine therapy as indicated. There was a 91% ovulatory response and 51% conception rate from therapy in cases of Type I PCO. In Type II PCO, adrenal suppressive therapy resulted in a 55% ovulatory response. The concept is supported that anovulation of ovarian origin as seen in PCO Type I responds to clomiphene therapy, while anovulation secondary to adrenal hyperandrogenization should be treated by adrenal suppressive therapy.This publication has 7 references indexed in Scilit:
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