Effect of General Anaesthesia on Renal Haemodynamics in the Rat
- 1 November 1979
- journal article
- research article
- Published by Portland Press Ltd. in Clinical Science
- Vol. 57 (5), 469-471
- https://doi.org/10.1042/cs0570469
Abstract
1. The effect of sodium pentobarbital and Inactin anaesthesia on renal haemodynamics in the rat was evaluated with radioactive microspheres 15 μm in diameter. 2. Both anaesthetic agents caused substantial decrements in total renal blood flow (sodium pentobarbital, −34%; Inactin, −24%) compared with unanaesthetized animals. 3. Measurements of renal function obtained in rats anaesthetized with either of these anaesthetic agents should be interpreted with caution.Keywords
This publication has 4 references indexed in Scilit:
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- Dextran as a radioactive microsphere suspending agent: severe hypotensive effect in ratAmerican Journal of Physiology-Heart and Circulatory Physiology, 1978
- Evaluation of methods of measuring glomerular and nutrient blood flow in rat kidneysAmerican Journal of Physiology-Heart and Circulatory Physiology, 1978
- Renal intracortical blood flow distribution, function and sodium excretion in response to saline loading of anesthetized and unanesthetized dogsPflügers Archiv - European Journal of Physiology, 1976