The stereochemistry of organometallic compounds. XXIII. Synthesis of a chiral diphosphinite (diphin) and evaluation of its use as a ligand for asymmetric catalysis

Abstract

(+)-(3S,4S)-Tetrahydrofuran-3,4-diyl bis(diphenylphosphinite) [(+)-diphin] has been synthesized and its efficiency as a ligand in asymmetric hydrogenation, hydrocyanation and hydroformylation compared with closely related diphosphine, diphosphinite and diphosphite ligands.