Effects of methotrexate on transfected DNA stability in mammalian cells.
Open Access
- 1 January 1990
- journal article
- research article
- Published by Taylor & Francis in Molecular and Cellular Biology
- Vol. 10 (1), 401-404
- https://doi.org/10.1128/mcb.10.1.401
Abstract
The chromosomal locations, amounts, and level of expression of transfected, amplified c-myc and dihydrofolate reductase sequences were measured in cells cultured in the presence and absence of methotrexate. These studies show that the location and amount of transfected sequences, as well as the level of expression, were more variable when the cells were cultured in methotrexate.This publication has 9 references indexed in Scilit:
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