The effects of high concentrations of an electrolyte on the swelling of non-metabolizing tissue slices
- 1 February 1971
- journal article
- Published by Wiley in The Journal of Physiology
- Vol. 212 (3), 641-653
- https://doi.org/10.1113/jphysiol.1971.sp009347
Abstract
1. Rat kidney cortical slices, with metabolism suppressed by iodoacetate, were incubated anaerobically at 26° C in hyperosmotic saline media. Changes in tissue composition with time, up to 12 hr, were studied. Despite initial shrinkage, gross swelling occurred, even in saline media of more than twice the concentration of normal extracellular fluid.Keywords
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