Determination of hydroquinone in skin-toning creams using high-performance liquid chromatography

Abstract

A simple, rapid reversed-phase HPLC method for the determination of hydroquinone in skin-toning creams is described that is suitable for routine use. The sample is dissolved in methanol or methanol-light petroleum and directly injected without further purification. The method successfully passed a ruggedness test and was applied to a range of 35 creams.