Histology of pulmonary arterial supply in pulmonary atresia with ventricular septal defect.
- 1 November 1979
- journal article
- research article
- Published by Wolters Kluwer Health in Circulation
- Vol. 60 (5), 1066-1074
- https://doi.org/10.1161/01.cir.60.5.1066
Abstract
A histologic study was performed on 22 specimens of pulmonary atresia with ventricular septal defect to 1) ascertain the existence of the main pulmonary artery; 2) distinguish the ductus arteriosus from the systemic collateral arteries (SCA); 3) establish the nutritive or functional nature of collateral circulation; and 4) evaluate the morphology of the distal pulmonary bed. Three cases had absent main pulmonary artery, one with and two without signs of infundibular septation. We suggest that absent main pulmonary artery may exist with both infundibular pulmonary atresia and persistent truncus arteriosus. SCAs have been found to have similar histological features as systemic muscular arteries of the same size--their medial muscular layer merges gradually into an elastic one at different depth inside the lungs. Injection of contrast material allowed us to demonstrate that these vessels are functional, since they inosculate into efficient pulmonary arteries ending in the respiratory units. When the distal p...This publication has 42 references indexed in Scilit:
- Pathogenesis of persistent truncus arteriosus in light of observations made in a dog embryo with the anomalyThe American Journal of Cardiology, 1978
- Development of the pulmonary circulation in ventricular septal defect: A quantitative structural studyThe American Journal of Cardiology, 1977
- Persistent truncus arteriosusThe American Journal of Cardiology, 1977
- Ventricular septal defect, solitary aortic trunk, and ductal origins of pulmonary arteriesAmerican Heart Journal, 1976
- “Agenesis” of ductus arteriosus associated with the syndrome of tetralogy of fallot and absent pulmonary valveThe American Journal of Cardiology, 1976
- The assessment of the arterial supply to the lungs in pseudotruncus arteriosus and truncus arteriosus Type IV in relation to surgical repairAmerican Heart Journal, 1974
- Hereditary defects of the conotruncal septum in keeshond dogs: Pathologic and genetic studiesThe American Journal of Cardiology, 1974
- Pulmonary atresia with cyanosis. Report of two cases with ventricular septal defect and increased pulmonary blood flow.Heart, 1971
- Selective catheterization of pulmonary or bronchial arteries in the preoperative assessment of pseudotruncus arteriosus and truncus arteriosus type IVThe American Journal of Cardiology, 1970
- The anatomy of common aorticopulmonary trunk (truncus arteriosus communis) and its embryologic implicationsThe American Journal of Cardiology, 1965