Demonstration of a Cytotoxic Agent in Gamma-irradiated Carbohydrate Solutions
- 1 January 1965
- journal article
- research article
- Published by Taylor & Francis in International Journal of Radiation Biology and Related Studies in Physics, Chemistry and Medicine
- Vol. 9 (6), 559-572
- https://doi.org/10.1080/09553006514550601
Abstract
Irradiated carbohydrate solutions have been found to be toxic to mammalian cells in vitro. For 1% solutions of dextrose or fructose added to the growth medium the effect is maximal after a dose of -105 rads. The toxic product, once formed, is heat-stable and persists after the heavy irradiation needed for sterilization for more than 6 months. Autoclaved dextrose and fructose solutions also show some cytotoxicity, but this is less pronounced in aged solutions.This publication has 18 references indexed in Scilit:
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