The plasma protease inhibitor system (Pi) of Standardbred horses
- 31 July 1984
- journal article
- research article
- Published by Wiley in Animal Blood Groups and Biochemical Genetics
- Vol. 15 (3), 191-206
- https://doi.org/10.1111/j.1365-2052.1984.tb01116.x
Abstract
The plasma protease inhibitor system (Pi) of standardbred horses was studied by thin-layer, high-voltage, acid polyacrylamide gel electrophoresis (pH 4.6) followed by protein staining and staining for trypsin and chymotrypsin inhibition. In addition to the 8 thoroughbred alleles (PiF, G, I, L, N, S1, S2, U), another 10 alleles, designated (PiH, J, K, O, P, Q, R, V, X, Z), were postulated to account for the 98 Pi types which were observed in standardbreds. Detailed inhibitory spectra of the new alleles were determined and further exceptions to the Pi1, Pi2 classification of Juneja et al. were found. Limited family data demonstrated the genetic nature of the new variants and confirmed the allelic inheritance of the new Pi variants.Keywords
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