Characterization of a Genetic Element Carrying the Macrolide Efflux Gene mef (A) in Streptococcus pneumoniae
- 1 September 2000
- journal article
- research article
- Published by American Society for Microbiology in Antimicrobial Agents and Chemotherapy
- Vol. 44 (9), 2585-2587
- https://doi.org/10.1128/aac.44.9.2585-2587.2000
Abstract
The mef (A) gene from a clinical isolate of Streptococcus pneumoniae exhibiting the M-type resistance to macrolides was found to be part of the 7,244-bp chromosomal element Tn 1207.1 , which contained 8 open reading frames. orf2 encodes a resolvase/invertase, and orf5 is a homolog of the macrolide-streptogramin B resistance gene msr (SA).Keywords
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