The use of doubly-labeled 13C-acetate in the study of streptolydigin biosynthesis.

Abstract
Using [13C2]acetate, the biosynthesis of streptolydigin [by Streptomyces lydicus] was investigated. A total of 4 acetate units are incorporated into the antibiotic, 3 into the acyl side chain and 1 into the tetramic acid portion.