A Case of Simultaneous Bilateral Germ Cell Tumors Arising from Cryptorchid Testes
- 1 August 1986
- journal article
- case report
- Published by Wolters Kluwer Health in Journal of Urology
- Vol. 136 (2), 470-472
- https://doi.org/10.1016/s0022-5347(17)44913-5
Abstract
We report a rare case of simultaneous bilateral testicular germ cell tumors arising from uncorrected cryptorchid testes. Each side had a different histological type, which consisted of pure high grade seminoma on the left side, and teratocarcinoma with choriocarcinoma and yolk sac tumor elements in addition to seminoma on the right side. Patients with cryptorchidism are known to have a higher risk of germ cell tumors. Genetic factors also may have a role in the oncogenesis in our patient, since his older brother had had a seminoma in the left cryptorchid testis previously. Both patients had the HLA-Aw24 antigen. The characteristics of familial testicular tumors are discussed.Keywords
This publication has 13 references indexed in Scilit:
- Testicular Seminoma in Father and Son. Case Report of Testicular Malignancies Occurring in Closely Related Family MembersAndrologia, 2009
- Familial patterns of testicular cancerUrology, 1984
- Dizygotic twinning, cryptorchism, and seminoma in a sibshipCancer, 1984
- Testicular Cancer in Two Brothers, One of Whom has AchondroplasiaBritish Journal of Urology, 1982
- Malignant testicular tumours in non-twin brothersPublished by Oxford University Press (OUP) ,1981
- Tumors of the testis in two brothers: A case reportJournal of Surgical Oncology, 1981
- Histologically Similar Testicular Neoplasms Occurring in BrothersJournal of Urology, 1980
- Concomitant Germ Cell Tumors in Monozygotic TwinsJournal of Urology, 1979
- Bilateral Testicular Tumors of Germ Cell OriginJournal of Urology, 1975
- AN ANALYSIS OF TUMORS IN MONOZYGOUS AND DIZYGOUS TWINSJournal of Heredity, 1940