Deoxyribonucleic acid strand breaks during freeze-drying and their repair in Escherichia coli
- 1 June 1977
- journal article
- research article
- Published by American Society for Microbiology in Journal of Bacteriology
- Vol. 130 (3), 1393-1396
- https://doi.org/10.1128/jb.130.3.1393-1396.1977
Abstract
Freeze-drying of E. coli cells caused strand breaks of DNA in radiation-sensitive and -resistant strains. In the radiation-resistant strain E. coli B/r, the damaged DNA was repaired after rehydration, but in the radiation-sensitive strain E. coli Bs-1, the damaged DNA was not repaired and the DNA was degraded. Repeated freeze-drying did not break the damaged DNA into smaller pieces.This publication has 20 references indexed in Scilit:
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