Clinical Use of the Urinary Uropepsin Determination in Medicine and Surgery

Abstract

MEASUREMENT of the excretion of pepsinogen in the urine (uropepsin) has been recommended as a quantitative test for gastric secretory function by a number of investigators.^{1 2 3 4 5 6 7} It has been applied clinically to the study of peptic ulcer, pernicious anemia and gastric cancer and has proved of considerable value in measuring the gastric response to ACTH stimulation and conditions of stress.^{8 , 9} The purpose of this presentation is to evaluate the clinical use of uropepsin excretion in a variety of gastrointestinal and endocrine diseases, as well as in the postoperative stomach in which gastric aspiration presents technical difficulties.The uropepsin excretion in . . .