Prognosis of fetuses with a cystic hygroma

Abstract

This paper reports our experience with 55 fetuses identified in utero to have a cystic hygroma. The outcome of fetuses with an isolated cystic hygroma, cystic hygroma with non‐immune hydrops, and cystic hygroma with multiple anomalies was evaluated. Approximately two‐thirds of karyotypes were aneuploid, and a strong association of septation and aneuploidy existed. Only five cases, four of which had isolated hygromas, came to term and resulted in live births. Two of these involved small non‐septated lesions which resolved in utero.