Geographic Differences in Sensitivity to Histoplasmin among Student Nurses

Abstract

Analysis, according to place of residence, of the histoplasmin reactions of 8,141 student nurses in connection with a study of early tuberculosis leads to the conclusions: Geography appears to be a very significant determining factor in the prevalence of positive reactors; an area of high prevalence of positive reactors exists in the eastern central part of the U.S.; and the frequency of positive reactors, in general, decreases with increasing distance from this area.