RELATIONSHIPS BETWEEN POSTRADIATION TREATMENTS WITH IODOACETATE AND LIGHT

Abstract

When ultraviolet irradiated spores of Streptomyces T12 were treated with iodoacetate for periods of up to six and a half hours and then photoreactivated, the proportion of survivors was greater than that for control spores similarly treated in distilled water. The frequencies of variant colonies from spores treated with iodoacetate and photoreactivated did not differ significantly from those obtained when spores were similarly treated in distilled water. The principal effect of iodoacetate treatment was inhibition of the loss of photoreversibility, as measured by the effect upon proportion of survivors.