Clinical studies with misonidazole.
- 1 June 1978
- journal article
- clinical trial
- Vol. 3, 286-9
Abstract
The preliminary details of a randomized clinical trial of misonidazole for the radiotherapy of Grades 3 and 4 cerebral astrocytoma are described. Plasma concentrations of misonidazole and its O-demethylated metabolite, determined by high-pressure liquid chromatography analysis, are reported for 8 patients with astrocytoma, 1 with carcinoma of the bronchus and 1 with carcinoma of the breast. In the latter case, tumour concentrations are also presented.This publication has 9 references indexed in Scilit:
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