CAFFEINE CONTRACTURE
- 1 June 1960
- journal article
- research article
- Published by Proceedings of the National Academy of Sciences in Proceedings of the National Academy of Sciences
- Vol. 46 (6), 897-903
- https://doi.org/10.1073/pnas.46.6.897
Abstract
Reports that caffeine activates cross-striated muscle which has been completely depolarized with isotonic K2SO4 and that caffeine can also activate without a significant change in membrane potential are confirmed. The conclusion, however, that depolarization is not an essential requirement of normal activation is unjustified since effective caffeine treatment leaves behind irreversible changes indicating that the caffeine response is far from being physiological.This publication has 13 references indexed in Scilit:
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