Nickel-catalysed substitution reactions of allylic compounds with soft nucleophiles: an efficient alternative to palladium catalysis

Abstract

Substitution reactions of allyl alcohol derivatives 1a–c with diethylamine, phenol and dimethyl malonate are efficiently carried out in the presence of Ni(dppb)₂(dppb = 1,2-diphenylphosphinobutane) as catalyst and ammonium salts or bases as promoters or co-reagents.