Glycosaminoglycans of Human Gingival Epithelium and Connective Tissue
- 1 January 1981
- journal article
- research article
- Published by Taylor & Francis in Connective Tissue Research
- Vol. 9 (2), 99-106
- https://doi.org/10.3109/03008208109160247
Abstract
The glycosaminoglycan (GAG) components of the proteoglycans (PG) in the epithelial and connective tissue extracellular compartments of human gingivae have been determined. Following proteolytic digestion of the separated tissues. GAG were identified electrophoretically. These were hyaluronic acid (HA), heparan sulfate (HS), dermatan sulfate (DS) and chondroitin-4 sulfate (ChS-4). Neither ChS-6 nor keratan sulfate (KS) was observed. Confirmation of the nature of the molecular species was obtained by the use of Streptomyces hyaluronidase, chondroitinase AC II and degradation with nitrous acid. Quantitatively, the major GAG component of the epithelial specimens was HS (59.6%), whilst DS (60.6%) constituted the major GAG of human gingival connective tissue.This publication has 42 references indexed in Scilit:
- The metabolism of proteoglycans and glycosaminoglycans in inflamed human gingivaJournal of Periodontal Research, 1979
- Constitutional Heterogeneity of the Glycosaminoglycans in Articular Cartilage ProteoglycansConnective Tissue Research, 1977
- Hyaluronate and Hyaluronidase in Morphogenesis and DifferentiationAmerican Zoologist, 1973
- The specific interaction of hyaluronic acid with cartilage proteoglycansBiochimica et Biophysica Acta (BBA) - General Subjects, 1972
- A fine structural study of divalent cation‐mediated epithelial union with connective tissue in human oral mucosaJournal of Anatomy, 1972
- Heparan sulfates of cultured cells. II. Acid-soluble and -precipitable species of different cell linesBiochemistry, 1971
- Heparan sulfates of cultured cells. I. Membrane-associated and cell-sap species in Chinese hamster cellsBiochemistry, 1971
- Cellular control of macromolecular synthesis: rates of synthesis of extracellular macromolecules during and after depletion by papainProceedings of the Royal Society of London. B. Biological Sciences, 1968
- On the interaction between polysaccharides and other macromolecules: II. The transport of globular particles through hyaluronic acid solutionsBiochimica et Biophysica Acta, 1963
- Water-Soluble Mucoproteins of the GingivaJournal of Dental Research, 1953