Morphogenesis of Yellow Fever Virus in Aedes aegypti Cultured Cells
- 1 September 1981
- journal article
- research article
- Published by American Society of Tropical Medicine and Hygiene in The American Journal of Tropical Medicine and Hygiene
- Vol. 30 (5), 1071-1077
- https://doi.org/10.4269/ajtmh.1981.30.1071
Abstract
The growth and intracytoplasmic development of two yellow fever virus strains (wild and French neurotropic) were studied in Aedes aegypti cells (clone C 17). Despite a longer period of latency for the vaccine virus, infected cells appeared similar. The cisternae of the rough endoplasmic reticulum (RER) were swollen and formed vesicles which contained the virus. This RER appeared to be the predominant locus of viral synthesis and maturation. Cytopathic effect appeared when the cells were filled with vesicles, and it was characterized by cell degeneration and lysis.This publication has 6 references indexed in Scilit:
- Morphogenesis of Yellow Fever Virus in Aedes aegypti Cultured CellsThe American Journal of Tropical Medicine and Hygiene, 1981
- Replication of Dengue-2 Virus in Aedes albopictus MosquitoesThe American Journal of Tropical Medicine and Hygiene, 1977
- Electron microscope study of the development of Japanese B encephalitis virus in porcine kidney stable (PS) cellsVirology, 1965
- ELECTRON MICROSCOPIC + IMMUNOFLUORESCENT OBSERVATIONS ON MONKEY LIVER + TISSUE CULTURE CELLS INFECTED WITH ASIBI STRAIN OF YELLOW FEVER VIRUS1964
- Electron microscopic study of spinal cord of mice infected with yellow fever virusJournal of Ultrastructure Research, 1963
- Demonstration of yellow fever virus with the electron microscopeVirology, 1962