Intentions to Participate in Genetics Research among African American Smokers
Open Access
- 1 January 2006
- journal article
- Published by American Association for Cancer Research (AACR) in Cancer Epidemiology, Biomarkers & Prevention
- Vol. 15 (1), 150-153
- https://doi.org/10.1158/1055-9965.epi-05-0437
Abstract
Although prior studies have shown that African American smokers are likely to carry some of the genetic variants associated with smoking risk, additional research with African American smokers is needed to replicate these findings. Limited information is available on interest in participating in research to identify genetic risk factors for smoking among African American smokers; therefore, the goals of the present study were to describe intentions to participate in smoking and genetics research, and to determine factors that are associated with participation intentions. Subjects were 128 African American male and female adult smokers. Sociodemographic characteristics, clinical factors, attitudes about genetic testing, and intentions to participate in genetics research were evaluated during a structured telephone interview. Overall, 58% of respondents reported that they would be very likely to participate in research to identify genetic risk factors for smoking. Greater beliefs about the benefits of participating in medical research (odds ratio, 3.17; 95% confidence interval, 1.45-6.94; P = 0.004) and fewer perceptions of the limitations and risks of genetic testing (odds ratio, 0.90; 95% confidence interval, 0.82-0.98; P = 0.01) had significant independent associations with reporting a high likelihood of participating in this type of research. Recruitment messages and protocols that address the benefits of research participation, as well as concerns about the limitations and risks of genetic testing, may enhance African American participation in research on genetics and smoking. (Cancer Epidemiol Biomarkers Prev 2006;(15)1:150–3)Keywords
This publication has 17 references indexed in Scilit:
- Treating Tobacco Dependence: State of the Science and New DirectionsJournal of Clinical Oncology, 2005
- The use of race variables in genetic studies of complex traits and the goal of reducing health disparities: A transdisciplinary perspective.American Psychologist, 2005
- Attitudes and beliefs concerning prostate cancer genetic screeningClinical Genetics, 2004
- Translating emerging research on the genetics of smoking into clinical practice: Ethical and social considerationsNicotine & Tobacco Research, 2004
- Participation in Cancer Clinical TrialsJAMA, 2004
- Racial and Ethnic Variations in Knowledge and Attitudes about Genetic TestingGenetic Testing, 2004
- Applying genetic approaches to the treatment of nicotine dependenceOncogene, 2002
- Perceptions of Genetics Research As Harmful to Society: Differences among Samples of African-Americans and European-AmericansGenetic Testing, 2002
- Intention to Participate in Predictive Genetic Testing for Hereditary Cancer: The Role of Attitude toward UncertaintyPsychology & Health, 2002
- BRCA1 testing in families with hereditary breast-ovarian cancer. A prospective study of patient decision making and outcomesPublished by American Medical Association (AMA) ,1996