Chromosomal assignments of genes for trypsin, chymotrypsin B, and elastase in mouse
- 1 July 1984
- journal article
- research article
- Published by Springer Nature in Somatic Cell and Molecular Genetics
- Vol. 10 (4), 377-383
- https://doi.org/10.1007/bf01535633
Abstract
The mouse genes for the serine proteases trypsin (Try-1,chymotrypsin B (Ctrb),and elastase (Ela-1)were chromosomally assigned using Southern blot hybridization of mouse × Chinese hamster cell hybrid DNA. cDNA probes for the three genes were hybridized to cell hybrid DNA cleaved with BamHI or HindIII and the segregation of Try-1, Ctrb,and Ela-1was correlated with the segregation of mouse chromosomes. Try-1is located on chromosome 6, Ctrbis on chromosome 8, and Ela-1is on chromosome 15. The three genes fall into three syntenic groups that are conserved in the mouse and human genomes.This publication has 21 references indexed in Scilit:
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