Linoleic acid levels in white blood cells, platelets, and serum of multiple sclerosis patients
- 1 October 1987
- journal article
- research article
- Published by Hindawi Limited in Acta Neurologica Scandinavica
- Vol. 76 (4), 241-245
- https://doi.org/10.1111/j.1600-0404.1987.tb03574.x
Abstract
We found a small but statistically significant reduction in the linoleic acid concentration of white blood cells and platelets in MS patients. The percent linoleic acid concentration (mean .+-. S.D.) in the white blood cells of 24 MS patients was 8.8 .+-. 1.8% as compared with 11.4 .+-. 4.9 in 24 age and sex-matched controls (p < 0.05). Platelet levels were 8.5 .+-. 2.4% and 10.6 .+-. 3.8% respectively (P < 0.05). Serum linoleic acid levels were not significantly different in the two groups. The possible role of linoleic acid in the pathogenesis of MS has yet to be defined.Keywords
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