Effect of Age Upon Glutamine Synthesis and Glutamine Amide Exchange of Rat Liver, Kidney and Testis

Abstract
As a preliminary study to the elucidation of the nature of increased protein synthesis in cancer and decreased synthesis with senescence, the variations with age in glutamine synthesis and amide exchange in liver, kidney and testis of the albino rat were ascertained. A natural inhibitor of these reactions was encountered. Limitations of the assay methods utilized are delineated.