Gastric Lymphoma and Helicobacter pylori

Abstract

In 1983, Warren and Marshall discovered a spiral urease-producing organism in the human stomach, later classified as Helicobacter pylori¹. H. pylori has been shown to be strongly associated with peptic ulcer disease, and antibiotic therapy to eradicate this organism is an important treatment for duodenal and gastric ulcers². In many countries, the prevalence of H. pylori infection in adults is 35 percent or more, although most infected people have no symptoms.H. pylori has also been associated with gastric carcinoma. Correa described four steps already taken to establish the association³. The first was to observe that H. . . .