Identification and quantitation of 1-arylpiperazines, metabolites resulting from side-chain cleavage of (4-substituted aryl-1-piperazinyl)alkyl heterocyclic derivatives in rat plasma and brain
- 1 January 1984
- journal article
- research article
- Published by Elsevier in Journal of Chromatography A
- Vol. 283 (JAN), 211-221
- https://doi.org/10.1016/s0021-9673(00)96256-3
Abstract
No abstract availableThis publication has 15 references indexed in Scilit:
- Disposition and metabolism of buspirone and its metabolite 1-(2-pyrimidinyl)-piperazine in the ratXenobiotica, 1983
- 1-m-Chlorophenylpiperazine is an active metabolite common to the psychotropic drugs trazodone, etoperidone and mepiprazoleJournal of Pharmacy and Pharmacology, 1982
- Plasma concentrations of trazodone and 1-(3-chlorophenyl)piperazine in man after a single oral dose of trazodoneJournal of Pharmacy and Pharmacology, 1982
- TrazodoneDrugs, 1981
- Determination of plasma and brain concentrations of trazodone and its metabolite, l-m-chlorophenylpiperazine, by gas-liquid chromatographyJournal of Chromatography A, 1981
- Structure-Activity Relationships in the Actions of 1-Phenyl-Piperazines on Brain Serotonin ReceptorsAdvances in Experimental Medicine and Biology, 1981
- Effects of m-chlorophenylpiperazine on receptor binding and brain metabolism of monoamines in ratsNeurochemistry International, 1981
- Structural relationships in the inhibition of [3H]serotonin binding to rat brain membranes in vitro by 1-phenyl-piperazinesBiochemical Pharmacology, 1980
- The comparative efficacy of buspirone and diazepam in the treatment of anxietyAmerican Journal of Psychiatry, 1979
- Psychosedative agents. 2. 8-(4-Substituted 1-piperazinylalkyl)-8-azaspiro[4.5]decane-7,9-dionesJournal of Medicinal Chemistry, 1972