Distribution of the insertion sequence IS1 in Gram-negative bacteria
- 1 February 1981
- journal article
- research article
- Published by Springer Nature in Nature
- Vol. 289 (5798), 609-612
- https://doi.org/10.1038/289609a0
Abstract
The distribution of the insertion sequence IS1 in various bacteria, particularly members of the family Enterobacteriaceae is reported. Comparision of the results with the phylogenetic relationship of these bacteria suggests that IS1 was transferred from one bacterium to another after their divergence and in some bacteria the copy number of IS1 increased by translocation. The increase in the number of copies of IS1 in bacteria may increase the probability of the genetic rearrangement responsible for the generation of resistance and enterotoxin plasmids, the existence of which is a serious problem in medical microbiology. [Bacteria studied included the gram-negative bacteria Escherichia coli, Serratia marcescens, Salmonella typhimurium, Edwardsiella tarda (E. anguillimortifera), Enterobacter aerogenes, Klebsiella aerogenes (K. pneumoniae), Proteus mirabilis, P. morganii, Shigella dysenteriae, S. sonnei, S. boydii, S. flexneri, Pseudomonas aeruginosa, Acinetobacter sp., Myxococcus xanthus, Erwinia amylovora, Caulobacter crescentus and the gram-positive bacterium Bacillus subtilis.].Keywords
This publication has 24 references indexed in Scilit:
- Plasmids containing insertion elements are potential transposons.Proceedings of the National Academy of Sciences, 1980
- DNA sequence of the transposable element IS1Molecular Genetics and Genomics, 1979
- The transposon Tn9 generates a 9 bp repeated sequence during integrationCell, 1978
- Nucleotide sequence of an insertion element, IS1.Proceedings of the National Academy of Sciences, 1978
- Site specific recombination involved in the generation of small plasmidsMolecular Genetics and Genomics, 1978
- Transposable genetic elements as agents of gene instability and chromosomal rearrangementsNature, 1977
- Plaque forming specialized transducing phage P1: Isolation of P1CmSmSu, a precursor of P1CmMolecular Genetics and Genomics, 1977
- Acquisition of a determinant for chloramphenicol resistance by coliphage lambda.Proceedings of the National Academy of Sciences, 1975
- Polar mutations in lac, gal and phage λ consist of a few IS-DNA sequences inserted with either orientationMolecular Genetics and Genomics, 1972
- Two kinds of insertions in bacterial genesMolecular Genetics and Genomics, 1972