PERLÈCHE IN ADULTS

Abstract
Yeasts and yeastlike organisms have been advanced as the cause of a diverse group of diseases. The latest of these is perlèche, for which Finnerud1has established a strong case. He has been the only one to reproduce the disease experimentally with recovered organisms. Skolnik2reported five isolated cases in adults from which cryptococci were cultivated; Becker and Ritchie3recovered the "thrushfungus" from one of six cases in adults. Four additional, isolated, consecutive cases in adults from which Monilia was recovered are herein reported. REPORT OF CASES4 Case1.—A man, aged 48, sought advice because of trouble with the corners of the mouth of one month's duration. Examination showed bilateral, wedge-shaped, deeply fissured areas of dermatitis. A portion of the process extended over the mucous membranes medially 10 mm. from the commissures; it resembled leukoplakia. The patient's upper teeth had been extracted, but