A monoclonal anti‐C4d that demonstrates a specificity related to anti‐Ch
- 8 July 1986
- journal article
- research article
- Published by Wiley in Transfusion
- Vol. 26 (4), 370-374
- https://doi.org/10.1046/j.1537-2995.1986.26486262748.x
Abstract
A monoclonal anti-C4d reagent, L003, agglutinated untreated and trypsin-treated C4A Rodgers(Rg)- and C4B Chido(Ch)-coated red cells. Inhibition of the agglutination regardless of the Rg/Ch phenotype of the C4 coat, showed Ch specificity, more precisely for the Ch1 determinant. C4A allotypes that express Ch1 and Ch3 rather than Rg1 and Rg2, and C4B allotypes that express Rg1 rather than Ch1, Ch2, or Ch3 confirmed that the inhibition specificity in serologic tests was anti-Ch1 and not anti-C4B.This publication has 26 references indexed in Scilit:
- ‘Partial Inhibition’ of Anti‐Rg and Anti‐Ch ReagentsVox Sanguinis, 1985
- ‘Partial Inhibition’ of Anti‐Rg and Anti‐Ch Reagents.Vox Sanguinis, 1985
- C4 Polymorphism: Use of a Monoclonal Antibody to Distinguish C4A and C4B Locus ProductsVox Sanguinis, 1984
- C4 AND HLA HAPLOTYPES ASSOCIATED WITH PARTIAL INHIBITION OF ANTI‐RG AND ANTI‐CHInternational Journal of Immunogenetics, 1984
- Primary sequence differences between Chido and Rodgers variants of tryptic C4d of the human complement systemFEBS Letters, 1984
- Anti‐C4 in the Serum of a Transfused C4‐Deficient Patient with Systemic Lupus erythematosusVox Sanguinis, 1984
- A New Genetic Variant for Chido1Vox Sanguinis, 1984
- Amino acid sequence of a polymorphic segment from fragment C4d of human complement component C4FEBS Letters, 1983
- Immunochemical evidence for hybrid sialoglyco-proteins of human erythrocytesNature, 1981
- Preparation of Red Cells Coated with C4 and C3 Subcomponents and Production of Anti-C4d and Anti-C3dVox Sanguinis, 1976