A Double‐Blind Comparison of Meptazinol with Placebo in Postoperative Pain

Abstract

In a double-blind clinical trial, meptazinol (400 mg capsules) was significantly better than placebo in relieving postoperative pain in patients who had undergone total abdominal hysterectomy operations. Analgesic activity was assessed by patients rating their pain before and 1 h after the administration of each treatment, by sequential analysis of patient and investigator preference for treatment, and by calculating the time interval between doses of the 2 treatments.