Genetics of complement C4. Two homoduplication haplotypes C4S C4S and C4F C4F in a family
- 1 August 1982
- journal article
- research article
- Published by Springer Nature in Human Genetics
- Vol. 61 (1), 36-38
- https://doi.org/10.1007/bf00291328
Abstract
A family in which two homoduplicated C4 haplotypes (or supergenes) segregate is described. One haplotype C4F * 3 C4F *2.2 is composed of two C4F alleles and the other C4S * 5.1 C4S *1 of two C4S alleles. The C4F duplication haplotype is a partial inhibitor of the Rodgers antigen, and judged from our family and population material, it seems to be rather frequent and associated with HLAB *35, Bf * F, and HLAD/DR *1. The C4S duplication haplotype is Rg(a-) and is not identified in individuals without another S, Ch(a+) variant.This publication has 9 references indexed in Scilit:
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