Reduced transcriptional activity in individuals with IL-18 gene variants detected from functional but not association study
- 16 December 2005
- journal article
- clinical trial
- Published by Elsevier in Biochemical and Biophysical Research Communications
- Vol. 338 (2), 736-741
- https://doi.org/10.1016/j.bbrc.2005.10.012
Abstract
No abstract availableKeywords
This publication has 26 references indexed in Scilit:
- Genes for atopy and asthmaCurrent Opinion in Allergy and Clinical Immunology, 2001
- Cutting Edge: IL-18-Transgenic Mice: In Vivo Evidence of a Broad Role for IL-18 in Modulating Immune FunctionThe Journal of Immunology, 2001
- Interleukin-18 Regulates Both Th1 and Th2 ResponsesAnnual Review of Immunology, 2001
- Allergy and Allergic DiseasesNew England Journal of Medicine, 2001
- IL-18 induction of IgE: dependence on CD4+ T cells, IL-4 and STAT6Nature Immunology, 2000
- IL-18 Activates STAT3 in the Natural Killer Cell Line 92, Augments Cytotoxic Activity, and Mediates IFN-γ Production by the Stress Kinase p38 and by the Extracellular Regulated Kinases p44erk-1and p42erk-21The Journal of Immunology, 2000
- CONTRIBUTING FACTORS TO THE PATHOBIOLOGYClinics in Chest Medicine, 2000
- IFN-γ-Inducing Factor (IL-18) Increases Allergic Sensitization, Serum IgE, Th2 Cytokines, and Airway Eosinophilia in a Mouse Model of Allergic AsthmaThe Journal of Immunology, 2000
- IL-18, although antiallergic when administered with IL-12, stimulates IL-4 and histamine release by basophilsProceedings of the National Academy of Sciences, 1999
- IL-18: A TH1 -inducing, proinflammatory cytokine and new member of the IL-1 familyJournal of Allergy and Clinical Immunology, 1999