New insights into mechanisms of oxyradical and neutrophil mediated lung injury
- 1 December 1991
- journal article
- review article
- Published by Springer Nature in Klinische Wochenschrift
- Vol. 69 (21-23), 1009-1011
- https://doi.org/10.1007/bf01645148
Abstract
Acute lung injury in rats developing after systemic complement activation or deposition of IgG immune complexes is complement-dependent and oxygen radical-mediated. Recent findings have shown that a soluble complement receptor (sCRl) is capable of attenuating injury. Additional studies have also demonstrated requirements for the cytokines, TNFα, and for L-arginine derived products in lung injury that follows deposition of IgG immune complexes.Keywords
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