Active transport of proteins into the nucleus
- 26 November 1990
- journal article
- review article
- Published by Wiley in FEBS Letters
- Vol. 275 (1-2), 1-5
- https://doi.org/10.1016/0014-5793(90)81425-n
Abstract
Nuclear proteins are actively and posttranslationally transported across the nuclear envelope. This transport is highly selective process that can be divided into two steps, receptor-binding followed by translocation through the nuclear envelope. Receptor-binding is mediated by nuclear localization signals that have been identified in many nuclear proteins. Translocation is energy-dependent and occurs through the nuclear pore complex.Keywords
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