• 1 January 1977
    • journal article
    • research article
    • Vol. 32 (2), 151-159
Abstract
Conditions are described for the generation and detection of murine cytotoxic cells which lyse influenza virus-infected target cells [murine mastocytoma P-815 cells and mouse fibroblast L929 cells]. A number of criteria indicated that most and probably all of the activity was due to T [thymus-derived] cells. These criteria included the susceptibility of cytotoxic activity to treatment with anti-.theta. ascitic fluid plus complement and the enhancement of lysis when there was H-2 compatibility between donors of effector and virus-infected target cells.