ANTITHYROID DRUGS: III

Abstract

THE OBSCURITY of the fundamental disturbances in the body leading to the development of thyrotoxicosis has interfered with a direct approach in the therapy of this disease. Although much progress has been made in controlling it by surgical measures, a great deal is left to be desired, both as concerns the principles and the results of treatment. The ideal therapy is one which is simple, inexpensive, available to everyone, does not necessitate hospitalization, is not associated with significant toxic reactions and does not permit much invalidism. These ideals do not seem to be as reasonable an expectation with surgical treatment as with chemotherapy or physical therapy, but they must be developed to a greater extent. Recent contributions¹ to the physiology of the thyroid have led to a clearer understanding of some of the problems of thyrotoxicosis. PHYSIOLOGIC-CHEMICAL CONSIDERATIONS OF THYROID FUNCTION Whereas complete proof does not substantiate some of