Isolation of a Human Single Chain Antibody Fragment Against Oligomeric α-Synuclein that Inhibits Aggregation and Prevents α-Synuclein-induced Toxicity
- 7 March 2007
- journal article
- Published by Elsevier in Journal of Molecular Biology
- Vol. 368 (4), 1132-1144
- https://doi.org/10.1016/j.jmb.2007.02.089
Abstract
No abstract availableKeywords
This publication has 66 references indexed in Scilit:
- Isolating recombinant antibodies against specific protein morphologies using atomic force microscopy and phage display technologiesProtein Engineering, Design and Selection, 2006
- Monoclonal antibodies that target pathological assemblies of AβJournal of Neurochemistry, 2006
- Conformation‐Dependent Anti‐Amyloid Oligomer AntibodiesMethods in Enzymology, 2006
- Human single-chain Fv intrabodies counteract in situ huntingtin aggregation in cellular models of Huntington's diseaseProceedings of the National Academy of Sciences, 2001
- A Hydrophobic Stretch of 12 Amino Acid Residues in the Middle of α-Synuclein Is Essential for Filament AssemblyJournal of Biological Chemistry, 2001
- Reduced Neuritic Outgrowth and Cell Adhesion in Neuronal Cells Transfected with Human α-SynucleinMolecular and Cellular Neuroscience, 2001
- α-Synuclein Membrane Interactions and Lipid SpecificityJournal of Biological Chemistry, 2000
- Fiber diffraction of synthetic α-synuclein filaments shows amyloid-like cross-β conformationProceedings of the National Academy of Sciences, 2000
- A Drosophila model of Parkinson's diseaseNature, 2000
- Dopaminergic Loss and Inclusion Body Formation in α-Synuclein Mice: Implications for Neurodegenerative DisordersScience, 2000