Homology and non-homology at the yeast mating type locus
- 1 January 1981
- journal article
- research article
- Published by Springer Nature in Nature
- Vol. 289 (5795), 250-252
- https://doi.org/10.1038/289250a0
Abstract
Four mutations of the .alpha. mating type locus of S. cerevisiae were analyzed to determine their relationship to the a mating type locus. Mat.alpha.+ recombinants are produced by mat.alpha.2-/MATa but not by mat.alpha.1-/MATa diploids. MAT.alpha. and MATa thus contain regions of homology (coding for at least part of MAT.alpha.2) and regions of non-homology (coding for at least part of MAT.alpha.1), the genetic determinant for cell type is larger than the non-homologous sequence seen by DNA-DNA heteroduplexes and genetic analysis. The segment transposed in mating type interconversion includes both types of sequence.This publication has 16 references indexed in Scilit:
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