Cholesterol Biosynthesis: Mevalonate Synthesis Inhibited by Bile Salts
- 26 February 1965
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 147 (3661), 1038
- https://doi.org/10.1126/science.147.3661.1038
Abstract
Certain bile salts inhibit biosynthesis of mevalonate from acetate-2-C14 in normal rat liver homogenates. The physiological control of cholesterol biosynthesis is discussed.Keywords
This publication has 5 references indexed in Scilit:
- FEEDBACK CONTROL OF CHOLESTEROL SYNTHESIS IN MAN*JCI Insight, 1963
- DYNAMICS OF CHOLESTEROL METABOLISM, I. FACTORS REGULATING TOTAL STEROL BIOSYNTHESIS AND ACCUMULATION IN THE RATProceedings of the National Academy of Sciences, 1963
- Bacterial metabolism of mevalonic acid conversion to acetoacetateBiochemical and Biophysical Research Communications, 1962
- REDUCTION OF BETA-HYDROXY-BETA-METHYLGLUTARYL COENZYME-A TO MEVALONIC ACID1960
- THE BIOSYNTHESIS OF CHOLESTEROL FROM ACETATE-1-C14 BY CELLULAR FRACTIONS OF RAT LIVERJournal of Biological Chemistry, 1956