Abstract
Bradykinin induces a release of unsaturated fatty acids and of prosta-glandins from the perfused rat lung. This release is inhibited by chloro-quine, a phospholipase A inhibitor. Histamine has no stimulating effect on fatty acids production. It is suggested that prostaglandins release induced by bradykinin might depend on a phospholipase activation. (1) Avant grattage, une solution de BHT (1 % dans le chloroforme) est vaporisée sur la plaque afin d'eviter la peroxydation des acides gras polyinsatures.