The Efficacy of an Herbal Medicine, Carmint, on the Relief of Abdominal Pain and Bloating in Patients with Irritable Bowel Syndrome: A Pilot Study
- 26 July 2006
- journal article
- research article
- Published by Springer Nature in Digestive Diseases and Sciences
- Vol. 51 (8), 1501-1507
- https://doi.org/10.1007/s10620-006-9079-3
Abstract
Carmint contains total extracts of Melissa officinalis, Mentha spicata, and Coriandrum sativum, which have antispasmodic, carminative, and sedative effects. As abdominal pain/discomfort and bloating are commonly observed in patients with irritable bowel syndrome, we decided to evaluate the effectiveness of Carmint in relieving these symptoms in irritable bowel syndrome patients. We randomly assigned 32 irritable bowel syndrome patients to receive either Carmint or placebo, plus Loperamide or psyllium (based on their predominant bowel function), for 8 weeks. T-test analysis of the results showed that the severity and frequency of abdominal pain/discomfort were significantly lower in the Carmint group than the placebo group at the end of the treatment (P=0.016 and P=0.001, respectively), as were the severity and frequency of bloating (P=0.02 and P=0.002, respectively). This pilot study suggests that Carmint plus loperamide or Carmint plus psyllium (depending on the irritable bowel syndrome subtype) might be effective in these patients.Keywords
This publication has 24 references indexed in Scilit:
- Aromatherapy as a Safe and Effective Treatment for the Management of Agitation in Severe DementiaThe Journal of Clinical Psychiatry, 2002
- Functional bowel disorders and functional abdominal painGut, 1999
- Modulation of gastric sensory and motor functions by nitrergic and α2-adrenergic agents in humansGastroenterology, 1999
- Functional Gut Disorders: From Motility to Sensitivity Disorders. A Review of Current and Investigational Drugs for Their ManagementPharmacology & Therapeutics, 1998
- Comparison of Diet Composition in Women with and without Functional Bowel DisorderGastroenterology Nursing, 1994
- U. S. Householder survey of functional gastrointestinal disordersDigestive Diseases and Sciences, 1993
- Colonic Tone and Motility in Patients With Irritable Bowel SyndromeMayo Clinic Proceedings, 1992
- Role of loperamide and placebo in management of irritable bowel syndrome (IBS)Digestive Diseases and Sciences, 1984
- What is the benefit of coarse wheat bran in patients with irritable bowel syndrome?Gut, 1984
- Treating irritable bowel syndrome with peppermint oil.BMJ, 1979