Changing Patterns of Resistance of Certain Common Pathogenic Bacteria to Antimicrobial Agents

Abstract

DURING the past few years workers at the Thorndike Memorial Laboratory have collected a considerable number of data on the in vitro susceptibility of common pathogenic bacteria to the various antibiotics that have been generally available. On occasions when new antibiotics were under clinical trial, consecutive strains of different species obtained either in pure culture or as the predominant organisms in mixed cultures from clinical material were tested for susceptibility to those agents to define their antibacterial effect on organisms encountered in the hospital at that time. On other occasions special studies were carried out in which successive strains of . . .