Circadian Rhythm of Plasma 11-Hydroxycorticosteroids in Psychiatric Disorders
- 17 August 1968
- Vol. 3 (5615), 405-407
- https://doi.org/10.1136/bmj.3.5615.405
Abstract
Studies of the circadian rhythm in plasma 11-O.H.C.S. levels showed that a subgroup of affective psychotics had higher plasma 11-OHCS values as compared with schizophrenic and other psychotic subgroups, and a somewhat less regular rhythm. One patient with depression who was studied over 48-hour periods showed a reduction in plasma 11-OHCS levels with clinical recovery. An accentuated fall and rise in plasma 11-OHCS values in the night and early morning samples, respectively, was observed in the schizophrenic subgroup.Keywords
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