Time-Resolved Resonance Raman Spectroscopy of Hemoglobin Derivatives: Heme Structure Changes in 7 Nanoseconds
- 1 September 1978
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 201 (4358), 831-833
- https://doi.org/10.1126/science.684409
Abstract
Resonance Raman spectra of oxyhemoglobin, deoxyhemoglobin, carboxyhemoglobin, and the corresponding myoglobin derivatives have been obtained with 7-nanosecond laser pulses at 531.8 nanometers. The results suggest that no transient constraint of the heme group by the globin structure occurs on this time scale, and thus establish a temporal sequence for the early events that may participate in the stereochemical trigger mechanism of hemoglobin cooperativity.This publication has 12 references indexed in Scilit:
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