Our earlier experience at St. Mary's Hospital with diverticulitis of the large bowel has been reported in former articles.1 The clinical similarity of diverticulitis and carcinoma has been emphasized. The condition has been placed clearly on a definite pathologic basis, and the possibility of the development of carcinoma on diverticulitis has been demonstrated. A more detailed analysis of the symptoms and the physical findings in a group of personally observed cases has not, however, been made, and it is with the idea of determining whether or not a more or less definite clinical picture presents itself that this review is undertaken. From Jan. 1, 1902, to Jan. 1, 1912, twenty-seven operations for diverticulitis of the large bowel were performed at St. Mary's Hospital, Mayo Clinic, and the cases were studied clinically and pathologically. This number includes only those cases in which the operation was done primarily for this condition.