Color coded triarylmethyl protecting groups useful for deoxypolynucleotide synthesis
Open Access
- 11 March 1983
- journal article
- research article
- Published by Oxford University Press (OUP) in Nucleic Acids Research
- Vol. 11 (5), 1589-1599
- https://doi.org/10.1093/nar/11.5.1589
Abstract
Triarylmethyl groups having ditferent colors but similar chemical reactivities in acid were examined as potential aids for monitoring the stepwise addition of mononucleotides to a deoxy-oligonucleotide. The successful application of these protecting groups to deoxyoligonucleotide synthesis on polymer supports was demonstrated.Keywords
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