A System for the Simultaneous Chemical Synthesis of Different DNA Fragments on Solid Support
- 1 October 1986
- journal article
- research article
- Published by Mary Ann Liebert Inc in DNA
- Vol. 5 (5), 413-419
- https://doi.org/10.1089/dna.1986.5.413
Abstract
A mechanical apparatus for the simultaneous synthesis of different DNA fragments on solid support is described. This new system allows the use of different kinds of supports and is amenable to automation. Utilizing this apparatus the synthesis of DNA fragments can be speeded up considerably. The effectiveness of the system is demonstrated by the simultaneous synthesis of DNA fragments up to 36 nucleotides long using phosphoamidites as building blocks and controlled pore glass as solid support.This publication has 16 references indexed in Scilit:
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